|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
|
|
Deletion
|
20
(LD)
,
DE(PLK1608)
,
OCR70,L90-6 (LD 20-1_P/O & 20-2TC)
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
sad
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
sad
Search strains by all related name:
sad b1525 ECK1518 f470 JW5247 yneI
|
General information (Go to Linear View: )
|
|
Gene Name
|
sad
|
|
Alternative name
|
b1525,ECK1518,f470,JW5247,yneI
|
|
Location, Length
|
1,611,339 - 1,612,727
(
-
)
;
34.73
min
;
1389
(bp) ,
462
(aa)
|
|
Product
|
succinate semialdehyde dehydrogenase, NAD(P)+-dependent
|
|
Operon Name
|
sad
|
|
Note
|
putative aldehyde dehydrogenase
|
|
Function
|
putative enzyme; Not classified
|
|
Gene Ontology
|
GO:0008152
;
metabolic process ( yneI )
GO:0016491
;
oxidoreductase activity ( yneI )
|
|
PID
|
87081926
|
EC number
(KEGG Pathway)
|
1.2.1.24
|
|
SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
GABD_ECOLI
(
P25526
;
P78207; P78208; P78209
)
|
|
- Protein name
|
Succinate-semialdehyde dehydrogenase [NADP+]
|
|
- Synonyms
|
EC 1.2.1.16, SSDH
|
|
- Gene name
|
Name=gabD; OrderedLocusNames=b2661;
|
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Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
yneI
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Sheep Liver Class 1 Aldehyde Dehydrogenase With Nad Bound
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Aldehyde dehydrogenase-like protein yneI
|
|
PSI-BLAST
|
Retinal dehydrogenase 1
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
aldehyde dehydrogenase homolog b1525 - Escherichia coli
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
GLYCOSAMINOGLYCAN
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
ALDEHYDE_DEHYDR_CYS
|
|
MMBR References
|
J Bacteriol. 1988;170(2):991-4.
Cloning and expression of the Escherichia coli K-12 sad gene.
Marek LE, Henson JM.
(
3276667
)
|
Arch Microbiol. 1982;132(3):270-5.
An Escherichia coli mutant defective in the NAD-dependent succinate semialdehyde dehydrogenase.
Skinner MA, Cooper RA.
(
6756331
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MTITPATHAI SINPATGEQL SVLPWAGADD IENALQLAAA GFRDWRETNI DYRAEKLRDI GKALRARSEE
0071 MAQMITREMG KPINQARAEV AKSANLCDWY AEHGPAMLKA EPTLVENQQA VIEYRPLGTI LAIMPWNFPL
0141 WQVMRGAVPI ILAGNGYLLK HAPNVMGCAQ LIAQVFKDAG IPQGVYGWLN ADNDGVSQMI KDSRIAAVTV
0211 TGSVRAGAAI GAQAGAALKK CVLELGGSDP FIVLNDADLE LAVKAAVAGR YQNTGQVCAA AKRFIIEEGI
0281 ASAFTERFVA AAAALKMGDP RDEENALGPM ARFDLRDELH HQVEKTLAQG ARLLLGGEKM AGAGNYYPPT
0351 VLANVTPEMT AFREEMFGPV AAITIAKDAE HALELANDSE FGLSATIFTT DETQARQMAA RLECGGVFIN
0421 GYCASDARVA FGGVKKSGFG RELSHFGLHE FCNIQTVWKD RI
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 agcattctcg attcgtgaat aagtggctta
-070 atattattca ttttaaagca agagtaaatc tgcgtatctt cataccatga ctcataaagg agataccccg
0001 atgaccatta ctccggcaac tcatgcaatt tcgataaatc ctgccacggg tgaacaactt tctgtgctgc
0071 cgtgggctgg cgctgacgat atcgaaaacg cacttcagct ggcggcagca ggctttcgcg actggcgcga
0141 gacaaatata gattatcgtg ctgaaaaact gcgtgatatc ggtaaggctc tgcgcgctcg tagcgaagaa
0211 atggcgcaaa tgatcacccg cgaaatgggc aaaccaatca accaggcgcg cgctgaagtg gcgaaatcgg
0281 cgaatttgtg tgactggtat gcagaacatg gtccggcaat gctgaaggcg gaacctacgc tggtggaaaa
0351 tcagcaggcg gttattgagt atcgaccgtt ggggacgatt ctggcgatta tgccgtggaa ttttccgtta
0421 tggcaggtga tgcgtggcgc tgttcccatc attcttgcag gtaacggcta cttacttaaa catgcgccga
0491 atgtgatggg ctgtgcacag ctcattgccc aggtgtttaa agatgcgggt atcccacaag gcgtatatgg
0561 ctggctgaat gccgacaacg acggtgtcag tcagatgatt aaagactcgc gcattgctgc tgtcacggtg
0631 accggaagtg ttcgtgcggg agcggctatt ggcgcacagg ctggagcggc actgaaaaaa tgcgtactgg
0701 aactgggcgg ttcggatccg tttattgtgc ttaacgatgc cgatctggaa ctggcggtga aagcggcggt
0771 agccggacgt tatcagaata ccggacaggt atgtgcagcg gcaaaacgct ttattatcga agagggaatt
0841 gcttcggcat ttaccgaacg ttttgtggca gctgcggcag ccttgaaaat gggcgatccc cgtgacgaag
0911 agaacgctct cggaccaatg gctcgttttg atttacgtga tgagctgcat catcaggtgg agaaaaccct
0981 ggcgcagggt gcgcgtttgt tactgggcgg ggaaaagatg gctggggcag gtaactacta tccgccaacg
1051 gttctggcga atgttacccc agaaatgacc gcgtttcggg aagaaatgtt tggccccgtt gcggcaatca
1121 ccattgcgaa agatgcagaa catgcactgg aactggctaa tgatagtgag ttcggccttt cagcgaccat
1191 ttttaccact gacgaaacac aggccagaca gatggcggca cgtctggaat gcggtggggt gtttatcaat
1261 ggttattgtg ccagcgacgc gcgagtggcc tttggtggcg tgaaaaagag tggctttggt cgtgagcttt
1331 cccatttcgg cttacacgaa ttctgtaata tccagacggt gtggaaagac cggatctgac gcgacatatt
1401 cagctctgat atactcgcag gtcttttcag acctgcggtc caggagtaga aagtggcagt cgccatggat
1471 aatgcaattt tagaaaaca
|
