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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
|
OCR35
(D)
,
OCR35-5
(D)
|
|
Related gene (W3110 PEC)
|
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Gene Search
|
Search MG1655 PEC by gene name:
ldcC
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Related strains
|
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Strains Search
|
Search strains by gene name:
ldcC
Search strains by all related name:
ldcC b0186 ECK0185 JW0181 ldc LDC2 ldcH
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General information (Go to Linear View: )
|
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Gene Name
|
ldcC
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Alternative name
|
b0186,ECK0185,JW0181,ldc,LDC2,ldcH
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Location, Length
|
209,679 - 211,820
(
+
)
;
4.52
min
;
2142
(bp) ,
713
(aa)
|
|
Product
|
lysine decarboxylase 2, constitutive
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Operon Name
|
ldcC
|
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Note
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GO_process: GO:0006096 - glycolysis; GO_process: GO:0016052 - carbohydrate catabolic process
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Function
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enzyme; Energy metabolism, carbon: Pyruvate dehydrogenase
|
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Gene Ontology
|
GO:0003824
;
catalytic activity ( ldcC )
GO:0005515
;
protein binding ( ldcC )
GO:0005737
;
cytoplasm ( ldcC )
GO:0006520
;
amino acid metabolic process ( ldcC )
GO:0008923
;
lysine decarboxylase activity ( ldcC )
GO:0016829
;
lyase activity ( ldcC )
GO:0016831
;
carboxy-lyase activity ( ldcC )
GO:0030170
;
pyridoxal phosphate binding ( ldcC )
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PID
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1786384
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EC number
(KEGG Pathway)
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4.1.1.18
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
ldcC
(
EG13219
)
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Number of removed
|
0 aa cleaved
|
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SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
DCLZ_ECOLI
(
P52095
;
P78299
)
|
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- Protein name
|
Lysine decarboxylase, constitutive
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- Synonyms
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EC 4.1.1.18, LDC
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- Gene name
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Name=ldcC; Synonyms=ldcH, ldc; OrderedLocusNames=b0186;
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MMBR References
|
J Bacteriol. 1997;179:4486-4492
Characterization of a second lysine decarboxylase isolated from Escherichia coli.
Kikuchi, Y., H. Kojima, T. Tanaka, Y. Takatsuka, and Y. Kamio.
|
GenBank submission D49445. 1995
Yamamoto, Y.
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Genes Genet Syst. 1997;72(3):167-72.
The Escherichia coli ldcC gene encodes another lysine decarboxylase, probably a constitutive enzyme.
Yamamoto Y, Miwa Y, Miyoshi K, Furuyama J, Ohmori H.
(
9339543
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MNIIAIMGPH GVFYKDEPIK ELESALVAQG FQIIWPQNSV DLLKFIEHNP RICGVIFDWD EYSLDLCSDI
0071 NQLNEYLPLY AFINTHSTMD VSVQDMRMAL WFFEYALGQA EDIAIRMRQY TDEYLDNITP PFTKALFTYV
0141 KERKYTFCTP GHMGGTAYQK SPVGCLFYDF FGGNTLKADV SISVTELGSL LDHTGPHLEA EEYIARTFGA
0211 EQSYIVTNGT STSNKIVGMY AAPSGSTLLI DRNCHKSLAH LLMMNDVVPV WLKPTRNALG ILGGIPRREF
0281 TRDSIEEKVA ATTQAQWPVH AVITNSTYDG LLYNTDWIKQ TLDVPSIHFD SAWVPYTHFH PIYQGKSGMS
0351 GERVAGKVIF ETQSTHKMLA ALSQASLIHI KGEYDEEAFN EAFMMHTTTS PSYPIVASVE TAAAMLRGNP
0421 GKRLINRSVE RALHFRKEVQ RLREESDGWF FDIWQPPQVD EAECWPVAPG EQWHGFNDAD ADHMFLDPVK
0491 VTILTPGMDE QGNMSEEGIP AALVAKFLDE RGIVVEKTGP YNLLFLFSIG IDKTKAMGLL RGLTEFKRSY
0561 DLNLRIKNML PDLYAEDPDF YRNMRIQDLA QGIHKLIRKH DLPGLMLRAF DTLPEMIMTP HQAWQRQIKG
0631 EVETIALEQL VGRVSANMIL PYPPGVPLLM PGEMLTKESR TVLDFLLMLC SVGQHYPGFE TDIHGAKQDE
0701 DGVYRVRVLK MAG
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 AATTCGCAAA AGTTCTGAAA AAGGGTCACT
-070 TCGGTGGCCC TTTTTTATCG CCACGGTTTG AGCAGGCTAT GATTAAGGAA GGATTTTCCA GGAGGAACAC
0001 atgaacatca ttgccattat gggaccgcat ggcgtctttt ataaagatga gcccatcaaa gaactggagt
0071 cggcgctggt ggcgcaaggc tttcagatta tctggccaca aaacagcgtt gatttgctga aatttatcga
0141 gcataaccct cgaatttgcg gcgtgatttt tgactgggat gagtacagtc tcgatttatg tagcgatatc
0211 aatcagctta atgaatatct cccgctttat gccttcatca acacccactc gacgatggat gtcagcgtgc
0281 aggatatgcg gatggcgctc tggttttttg aatatgcgct ggggcaggcg gaagatatcg ccattcgtat
0351 gcgtcagtac accgacgaat atcttgataa cattacaccg ccgttcacga aagccttgtt tacctacgtc
0421 aaagagcgga agtacacctt ttgtacgccg gggcatatgg gcggcaccgc atatcaaaaa agcccggttg
0491 gctgtctgtt ttatgatttt ttcggcggga atactcttaa ggctgatgtc tctatttcgg tcaccgagct
0561 tggttcgttg ctcgaccaca ccgggccaca cctggaagcg gaagagtaca tcgcgcggac ttttggcgcg
0631 gaacagagtt atatcgttac caacggaaca tcgacgtcga acaaaattgt gggtatgtac gccgcgccat
0701 ccggcagtac gctgttgatc gaccgcaatt gtcataaatc gctggcgcat ctgttgatga tgaacgatgt
0771 agtgccagtc tggctgaaac cgacgcgtaa tgcgttgggg attcttggtg ggatcccgcg ccgtgaattt
0841 actcgcgaca gcatcgaaga gaaagtcgct gctaccacgc aagcacaatg gccggttcat gcggtgatca
0911 ccaactccac ctatgatggc ttgctctaca acaccgactg gatcaaacag acgctggatg tcccgtcgat
0981 tcacttcgat tctgcctggg tgccgtacac ccattttcat ccgatctacc agggtaaaag tggtatgagc
1051 ggcgagcgtg ttgcgggaaa agtgatcttc gaaacgcaat cgacccacaa aatgctggcg gcgttatcgc
1121 aggcttcgct gatccacatt aaaggcgagt atgacgaaga ggcctttaac gaagccttta tgatgcatac
1191 caccacctcg cccagttatc ccattgttgc ttcggttgag acggcggcgg cgatgctgcg tggtaatccg
1261 ggcaaacggc tgattaaccg ttcagtagaa cgagctctgc attttcgcaa agaggtccag cggctgcggg
1331 aagagtctga cggttggttt ttcgatatct ggcaaccgcc gcaggtggat gaagccgaat gctggcccgt
1401 tgcgcctggc gaacagtggc acggctttaa cgatgcggat gccgatcata tgtttctcga tccggttaaa
1471 gtcactattt tgacaccggg gatggacgag cagggcaata tgagcgagga ggggatcccg gcggcgctgg
1541 tagcaaaatt cctcgacgaa cgtgggatcg tagtagagaa aaccggccct tataacctgc tgtttctctt
1611 tagtattggc atcgataaaa ccaaagcaat gggattattg cgtgggttga cggaattcaa acgctcttac
1681 gatctcaacc tgcggatcaa aaatatgcta cccgatctct atgcagaaga tcccgatttc taccgcaata
1751 tgcgtattca ggatctggca caagggatcc ataagctgat tcgtaaacac gatcttcccg gtttgatgtt
1821 gcgggcattc gatactttgc cggagatgat catgacgcca catcaggcat ggcaacgaca aattaaaggc
1891 gaagtagaaa ccattgcgct ggaacaactg gtcggtagag tatcggcaaa tatgatcctg ccttatccac
1961 cgggcgtacc gctgttgatg cctggagaaa tgctgaccaa agagagccgc acagtactcg attttctact
2031 gatgctttgt tccgtcgggc aacattaccc cggttttgaa acggatattc acggcgcgaa acaggacgaa
2101 gacggcgttt accgcgtacg agtcctaaaa atggcgggat aaCTTGCCAG AGCGGCTTCC GGGCGAGTAA
2171 CGTGCTGTTA ACAAATAAAG GAGACGTTAT GCTGGGTTTA AAACAGGTTC ACCATATTGC GATTATTGCG
2241 AC
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