MG1655
W3110
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Gene Report : sdiA
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion LD3-5-1 (LD)  ,  OCL78 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  sdiA
Related strains
     Strains Search Search strains by gene name:  sdiA   Search strains by all related name:  sdiA b1916 ECK1915 JW1901 uvrX

General information  (Go to Linear View:)
 Gene Name sdiA  
 Alternative name b1916,ECK1915,JW1901,uvrX  
 Location, Length 1,994,134 - 1,994,856 (  -  ) ;   42.98 min ; 723 (bp) ,   240 (aa) Go to Linear View
 Product quorum-sensing transcriptional activator  
 Operon Name sdiA  
 Note transcriptional regulator of ftsQAZ gene cluster; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_process: GO:0006350 - transcription  
 Function regulator; Cell division  
 Gene Ontology GO:0003677 ; DNA binding ( sdiA )
GO:0003700 ; transcription factor activity ( sdiA )
GO:0005622 ; intracellular ( sdiA )
GO:0006350 ; transcription ( sdiA )
GO:0006355 ; regulation of transcription, DNA-dependent ( sdiA )
GO:0007049 ; cell cycle ( sdiA )
GO:0043565 ; sequence-specific DNA binding ( sdiA )
GO:0051301 ; cell division ( sdiA )
 PID 1788224  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) SDIA_ECOLI ( P07026 ; P76313 )
    -  Protein name Regulatory protein sdiA.  
    -  Synonyms  
    -  Gene name Name=sdiA; OrderedLocusNames=b1916;  

 Linear View (Whole Mode)
View Location
   1985.0  –  2010.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP sdiA (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Solution Structure Of E Coli Sdia1-171  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Regulatory protein sdiA  
         PSI-BLAST Regulatory protein sdiA
    nr     (database updated : 2007.02.20 )
         BLAST DNA-binding transcriptional activator [Escherichia coli K12]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    HTH_LUXR_FAMILY     

Other Cross-Reference
    COG COG2771K 
    EcoCyc sdiA 

MMBR References
J Bacteriol. 1996;178:2742-2748
An extracellular factor regulates expression of sdiA, a transcriptional activator of cell division genes in Escherichia coli.
Garcia-Lara, J., L. H. Shang, and L. I. Rothfield.
EMBO J. 1991;10:3363-3372
A factor that positively regulates cell division by activating transcription of the major cluster of essential cell division genes of Escherichia coli.
Wang, X. D., P. A. de Boer, and L. I. Rothfield.

Sequences
Amino acid
FASTA format
0001 MQDKDFFSWR RTMLLRFQRM ETAEEVYHEI ELQAQQLEYD YYSLCVRHPV PFTRPKVAFY TNYPEAWVSY 
0071 YQAKNFLAID PVLNPENFSQ GHLMWNDDLF SEAQPLWEAA RAHGLRRGVT QYLMLPNRAL GFLSFSRCSA 
0141 REIPILSDEL QLKMQLLVRE SLMALMRLND EIVMTPEMNF SKREKEILRW TAEGKTSAEI AMILSISENT 
0211 VNFHQKNMQK KINAPNKTQV ACYAAATGLI 

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             cattgcctga ataatataaa ttatatataa 
-070 atcttattta tgtgatagtt tgaattatca ttataaatga tactcactct caggggcgtt gcggtttact 
0001 atgcaggata aggatttttt cagctggcgt cgcacgatgc tgttgcgttt tcagaggatg gagaccgcag 
0071 aagaggtcta ccatgaaatt gagcttcagg ctcagcagct ggagtacgat tactattcgt tatgtgtccg 
0141 ccacccggta ccattcactc gacctaaagt ggctttttac accaattacc ctgaggcgtg ggttagttat 
0211 tatcaggcaa aaaactttct cgcaattgat ccggtgctga accctgaaaa ctttagtcag ggccatttaa 
0281 tgtggaatga tgacttattc agcgaagcac agccgttatg ggaagccgcg cgcgcacatg gtttacgccg 
0351 cggtgtcact cagtatttaa tgctgccaaa ccgggcgctg ggctttttgt ccttttcccg ttgcagcgcg 
0421 cgcgaaatac ccattcttag tgatgaactg caattaaaaa tgcagttact ggtgcgcgaa agtctgatgg 
0491 ctctgatgcg tttaaatgat gaaatagtga tgacgccaga gatgaatttc agcaagcgcg aaaaagaaat 
0561 tctgaggtgg acggcggaag ggaaaacatc agcagagata gcgatgattt tgtcaatctc tgagaatacg 
0631 gtcaatttcc accagaaaaa catgcagaaa aaaattaatg caccaaataa gacccaggtt gcctgttacg 
0701 cggccgctac tggcttaatt tgatctcttt tctgtcctgc gtgccagatg caaaaaccgg ctgaaaggca 
0771 cgctatcagc cggttttata ttactgacgg taggcttgtt taatttgctt aac