MG1655
W3110
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Gene Report : napC
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Biochem J. 1998;334 (Pt 2):355-65.
Transcriptional control and essential roles of the Escherichia coli ccm gene products in formate-dependent nitrite reduction and cytochrome c synthesis.
Tanapongpipat S, Reid E, Cole JA, Crooke H. ( 9716493 )
     Deletion 14 (LD)  ,  OCL70,72-3 (LD 14B_CRS) (D)  ,  OCL70,72-4 (LD 14C_P/O) (D)  ,  OCL72 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  napC
Related strains
     Strains Search Search strains by gene name:  napC   Search strains by all related name:  napC b2202 ECK2194 JW2190 yejX

General information  (Go to Linear View:)
 Gene Name napC  
 Alternative name b2202,ECK2194,JW2190,yejX  
 Location, Length 2,295,679 - 2,296,281 (  -  ) ;   49.48 min ; 603 (bp) ,   200 (aa) Go to Linear View
 Product quinol dehydrogenase, electron source for NapAB  
 Operon Name napFDAGHBC-ccmABCDEFGH  
 Note cytochrome c-type protein; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0009061 - anaerobic respiration; GO_process: GO:0017004 - cytochrome complex assembly  
 Function putative enzyme; Energy metabolism, carbon: Electron transport  
 Gene Ontology GO:0005506 ; iron ion binding ( napC )
GO:0005886 ; plasma membrane ( napC )
GO:0006118 ; electron transport ( napC )
GO:0006810 ; transport ( napC )
GO:0016020 ; membrane ( napC )
GO:0016021 ; integral to membrane ( napC )
GO:0020037 ; heme binding ( napC )
GO:0046872 ; metal ion binding ( napC )
 PID 1788530  
 EC number
  (KEGG Pathway)
 
 
SWISS-PROT  ( Show details )
  botton Entry name(Acc.no) NAPC_ECOLI ( P33932 )
    -  Protein name Cytochrome c-type protein napC.  
    -  Synonyms  
    -  Gene name Name=napC; OrderedLocusNames=b2202, c2739, z3459, ECs3091;  

 Linear View (Whole Mode)
View Location
   2285.0  –  2310.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP napC (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain C, Crystal Structure Of Cytochrome C Nitrite Reductase Nrfha Complex From Desulfovibrio Vulgaris  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Cytochrome c-type protein napC  
         PSI-BLAST Cytochrome c-type protein napC
    nr     (database updated : 2007.02.20 )
         BLAST cytochrome c-type protein [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE ASN_GLYCOSYLATION    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    CYTOCHROME_C     

Other Cross-Reference
    COG COG3005C 
    EcoCyc napC 

MMBR References
Mol Microbiol. 1996;19(3):467-81.
Escherichia coli K-12 genes essential for the synthesis of c-type cytochromes and a third nitrate reductase located in the periplasm.
Grove J, Tanapongpipat S, Thomas G, Griffiths L, Crooke H, Cole J. ( 8830238 )
J Bacteriol. 1991;173(19):6139-46.
Anaerobically expressed Escherichia coli genes identified by operon fusion techniques.
Choe M, Reznikoff WS. ( 1917846 )
J Bacteriol. 1993;175:1165-1172
Identification of the regulatory sequence of anaerobically expressed locus aeg-46.5.
Choe, M., and W. S. Reznikoff.

Sequences
Amino acid
FASTA format
0001 MGNSDRKPGL IKRLWKWWRT PSRLALGTLL LIGFVGGIVF WGGFNTGMEK ANTEEFCISC HEMRNTVYQE 
0071 YMDSVHYNNR SGVRATCPDC HVPHEFVPKM IRKLKASKEL YGKIFGVIDT PQKFEAHRLT MAQNEWRRMK 
0141 DNNSQECRNC HNFEYMDTTA QKSVAAKMHD QAVKDGQTCI DCHKGIAHKL PDMREVEPGF 

Nucleotide
FASTA format

View sequence out neighbor 100bp
-100                                             ttatttctgt ctgcaatgtc acgtaccgca 
-070 ggccgatacc gcgccaatcg tggggaatac ctttacccca tcaaaaggtt acgggaaata agaggttatt 
0001 atgggaaatt ctgaccgtaa gcctggtctg attaagcgcc tgtggaaatg gtggcgtacc cccagccgtc 
0071 tggcgctggg gacgctgctg ttgatcggtt ttgttggcgg catcgtcttc tggggtggct ttaacaccgg 
0141 gatggaaaaa gccaataccg aagagttctg cattagctgc cacgaaatgc gcaacacggt gtatcaggaa 
0211 tacatggatt ccgtgcacta caacaaccgt agcggcgtcc gtgcgacctg tccggattgt cacgttccgc 
0281 acgagtttgt gccgaagatg atacgcaagc tcaaagcaag taaagagctg tatggtaaaa tttttggcgt 
0351 tattgacacg ccgcagaaat ttgaagctca tcgtctgacg atggcacaga atgagtggcg gcgcatgaag 
0421 gacaataact cgcaggagtg ccgtaactgt cacaacttcg agtatatgga tacaaccgcc cagaaatcgg 
0491 ttgccgcgaa gatgcatgac caggcggtga aagatgggca aacctgtatt gattgccata aagggatagc 
0561 gcacaagctg cccgatatgc gtgaagtcga gccaggtttt taacagggtt attgcgtggg tatgcttgaa 
0631 gccagagagt tactttgtga gcgggatgaa cgaaccttat ttagtggctt gtcatttacg ctgaacgcag 
0701 gag