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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
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14
(LD)
,
OCL70,72-4 (LD 14C_P/O)
(D)
,
OCL71
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
rcsB
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Related strains
|
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Strains Search
|
Search strains by gene name:
rcsB
Search strains by all related name:
rcsB b2217 ECK2210 JW2205 viaA
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General information (Go to Linear View: )
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Gene Name
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rcsB
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Alternative name
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b2217,ECK2210,JW2205,viaA
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Location, Length
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2,314,199 - 2,314,849
(
+
)
;
49.88
min
;
651
(bp) ,
216
(aa)
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Product
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DNA-binding response regulator in two-component regulatory system with RcsC and YojN
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Operon Name
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rcsDB
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Note
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positive response regulator for colanic capsule biosynthesis, (sensor, RcsC); GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_function: GO:0016564 - transcription repressor activity; GO_function: GO:0042280 - cell surface antigen activity, host-interacting; GO_process: GO:0009242 - colanic acid biosynthetic process; GO_process: GO:0006350 - transcription
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Function
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regulator; Surface polysaccharides & antigens
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Gene Ontology
|
GO:0000156
;
two-component response regulator activity ( rcsB )
GO:0000160
;
two-component signal transduction system (phosphorelay) ( rcsB )
GO:0003677
;
DNA binding ( rcsB )
GO:0003700
;
transcription factor activity ( rcsB )
GO:0005515
;
protein binding ( rcsB )
GO:0005622
;
intracellular ( rcsB )
GO:0006350
;
transcription ( rcsB )
GO:0006355
;
regulation of transcription, DNA-dependent ( rcsB )
GO:0043565
;
sequence-specific DNA binding ( rcsB )
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PID
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1788546
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
|
RCSB_ECOLI
(
P14374
)
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- Protein name
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Capsular synthesis regulator component B.
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- Synonyms
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- Gene name
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OrderedLocusNames=b2217, c2760, z3476, ECs3106, SF2301, S2432;
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MMBR References
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J Bacteriol. 1992;174:3964-3971
The rcsB gene, a positive regulator of colanic acid biosynthesis in Escherichia coli, is also an activator of ftsZ expression.
Gervais, F. G., P. Phoenix, and G. R. Drapeau.
|
J Bacteriol. 1985;162(3):1111-9.
Regulation of capsular polysaccharide synthesis in Escherichia coli K-12: characterization of three regulatory genes.
Gottesman S, Trisler P, Torres-Cabassa AS.
(
3888955
)
|
Mol Microbiol. 1997;25(5):913-31.
Positive control of the two-component RcsC/B signal transduction network by DjlA: a member of the DnaJ family of molecular chaperones in Escherichia coli.
Kelley WL, Georgopoulos C.
(
9364917
)
|
J Bacteriol. 1996;178:1204-1206
Osmotic induction of capsule synthesis in Escherichia coli.
Sledjeski, D. D., and S. Gottesman.
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J Bacteriol. 1996;178:4273-4280
Identification of the promoter region for the colanic acid polysaccharide biosynthetic genes in Escherichia coli K-12.
Stout, V.
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J Bacteriol. 1991;173(5):1738-47.
RcsA, an unstable positive regulator of capsular polysaccharide synthesis.
Stout V, Torres-Cabassa A, Maurizi MR, Gutnick D, Gottesman S.
(
1999391
)
|
J Bacteriol. 1990;172(2):659-69.
RcsB and RcsC: a two-component regulator of capsule synthesis in Escherichia coli.
Stout V, Gottesman S.
(
2404948
)
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J Bacteriol. 1988;170(6):2599-611.
Fine-structure mapping and identification of two regulators of capsule synthesis in Escherichia coli K-12.
Brill JA, Quinlan-Walshe C, Gottesman S.
(
2836365
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MNNMNVIIAD DHPIVLFGIR KSLEQIEWVN VVGEFEDSTA LINNLPKLDA HVLITDLSMP GDKYGDGITL
0071 IKYIKRHFPS LSIIVLTMNN NPAILSAVLD LDIEGIVLKQ GAPTDLPKAL AALQKGKKFT PESVSRLLEK
0141 ISAGGYGDKR LSPKESEVLR LFAEGFLVTE IAKKLNRSIK TISSQKKSAM MKLGVENDIA LLNYLSSVTL
0211 SPADKD
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 GAACATCTGA TTCGTGAGAA GGATGTTCCA
-070 GGAATAGAAA AATACATCAG CGACATTGAC AGTTATGTCA AGAGCTTGCT GTAGCAAGGT AGCCTATTAC
0001 atgaacaata tgaacgtaat tattgccgat gaccatccga tagtcttgtt cggtattcgc aaatcacttg
0071 agcaaattga gtgggtgaat gttgtcggcg aatttgaaga ctctacagca ctgatcaaca acctgccgaa
0141 actggatgcg catgtgttga ttaccgatct ctccatgcct ggcgataagt acggcgatgg cattacctta
0211 atcaagtaca tcaagcgcca tttcccaagc ctgtcgatca ttgttctgac tatgaacaac aacccggcga
0281 ttcttagtgc ggtattggat ctggatatcg aagggatcgt gctgaaacaa ggtgcaccga ccgatctgcc
0351 gaaagctctc gccgcgctgc agaaagggaa gaaatttacc ccggaaagcg tttctcgcct gttggaaaaa
0421 atcagtgctg gtggttacgg tgacaagcgt ctctcgccaa aagagagtga agttctgcgc ctgtttgcgg
0491 aaggcttcct ggtgaccgag atcgctaaaa agctgaaccg cagtattaaa accatcagta gccagaagaa
0561 atctgcgatg atgaagctgg gtgtcgagaa cgatatcgcc ctgctgaatt atctctcttc agtgacctta
0631 agtccggcag ataaagacta aTCACCTGTA GGCCAGATAA GACGCGTTAG TGTCTTATCT GGCATTTGCA
0701 CCGATTGCCG GATGCGGCGT AAACGCCTTA TCCGGCCTAC GATTCCCATT A
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