MG1655
W3110
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Gene Report : kdsC
PEC Original Annotations
Essentiality
     Class essential
     References (PMID)
J Biol Chem. 2003;278(20):18117-23.
Escherichia coli YrbI is 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase.
Wu J, Woodard RW. ( 12639950 )
     Deletion OCL28-11 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  kdsC
Related strains
     Strains Search Search strains by gene name:  kdsC   Search strains by all related name:  kdsC b3198 ECK3187 JW3165 o188 yrbI yrbJ

General information  (Go to Linear View:)
 Gene Name kdsC  
 Alternative name b3198,ECK3187,JW3165,o188,yrbI,yrbJ  
 Location, Length 3,340,295 - 3,340,861 (  +  ) ;   71.99 min ; 567 (bp) ,   188 (aa) Go to Linear View
 Product 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase  
 Operon Name kdsC-lptC  
 Note  
 Function  
 Gene Ontology GO:0000287 ; magnesium ion binding ( kdsC )
GO:0009103 ; lipopolysaccharide biosynthetic process ( kdsC )
GO:0016787 ; hydrolase activity ( kdsC )
GO:0019143 ; 3-deoxy-manno-octulosonate-8-phosphatase activity ( kdsC )
 PID 2367202  
 EC number
  (KEGG Pathway)   		3.1.3.45  
SWISS-PROT  ( Show details [ 1 more] )
  botton Entry name(Acc.no) KDSC_ECOLI ( P45396 ; P45398 )
    -  Protein name 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase  
    -  Synonyms EC 3.1.3.45, KDO 8-P phosphatase  
    -  Gene name Name=kdsC; OrderedLocusNames=b3198, z4561, ECs4077;  

 Linear View (Whole Mode)
View Location
   3330.0  –  3355.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP kdsC (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Structure Of The Cobalt-Bound Form Of The Deoxy-D-Mannose- Octulosonate 8-Phosphate Phosphatase (Yrbi) From Haemophilus Influenzae (Hi1679)  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase)  
         PSI-BLAST Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
    nr     (database updated : 2007.02.20 )
         BLAST 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase [Escherichia coli O157:H7 EDL933]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    AMIDATION     

Other Cross-Reference
    COG COG1778R 
    EcoCyc kdsC 

Sequences
Amino acid
FASTA format 
0001 MSKAGASLAT CYGPVSADVI AKAENIRLLI LDVDGVLSDG LIYMGNNGEE LKAFNVRDGY GIRCALTSDI 
0071 EVAIITGRKA KLVEDRCATL GITHLYQGQS NKLIAFSDLL EKLAIAPENV AYVGDDLIDW PVMEKVGLSV 
0141 AVADAHPLLI PRADYVTRIA GGRGAVREVC DLLLLAQGKL DEAKGQSI
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             CCTCCGTGAT GGTTGCCGAT GGCGACCATT 
-070 TACTCGGTGT GTTACATATG CATGATTTAC TGCGTGCAGG CGTAGTGTAA AGATTCAAGG ATAAACAACA 
0001 atgagcaaag caggtgcgtc gcttgcgacc tgttacggcc ctgtcagcgc cgacgttata gcaaaagcag 
0071 agaacattcg tctgctgatc ctcgatgtcg atggcgtact gtcagatggc ctgatttata tgggcaataa 
0141 tggcgaagag ctgaaagcgt tcaatgttcg tgacggttat ggcattcgtt gtgcgctcac ctctgatatt 
0211 gaagtcgcta tcattaccgg gcgaaaggct aaactggtag aagatcgttg tgccacattg gggatcactc 
0281 acttgtatca ggggcagtca aacaaactga tcgcctttag cgatctgctg gaaaaactgg cgattgcccc 
0351 ggaaaatgtg gcttatgtcg gcgatgatct catcgactgg ccggtaatgg aaaaagtggg tttaagcgtc 
0421 gccgtggccg atgcgcatcc actgttgatc ccgcgcgccg attacgtgac gcgcattgct ggcggtcgtg 
0491 gcgcagtgcg cgaagtttgc gacttattac tcctggcgca gggcaaactg gatgaagcca aagggcaatc 
0561 gatatgaGTA AAGCCAGACG TTGGGTTATC ATTGTGCTAT CACTGGCGGT TCTGGTGATG ATCGGCATTA 
0631 ATATGGCCGA AAAAGACGAT ACCGCCCAGG TGGTCGT