MG1655
W3110
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Gene Report : nanT
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
     Deletion OCL27 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  nanT
Related strains
     Strains Search Search strains by gene name:  nanT   Search strains by all related name:  nanT b3224 ECK3213 f506 JW3193

General information  (Go to Linear View:)
 Gene Name nanT  
 Alternative name b3224,ECK3213,f506,JW3193  
 Location, Length 3,369,106 - 3,370,596 (  -  ) ;   72.62 min ; 1491 (bp) ,   496 (aa) Go to Linear View
 Product sialic acid transporter  
 Operon Name nanATEK-yhcH  
 Note GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0046349 - amino sugar biosynthetic process  
 Function transport; Murein sacculus, peptidoglycan  
 Gene Ontology GO:0005215 ; transporter activity ( nanT )
GO:0005351 ; sugar:hydrogen ion symporter activity ( nanT )
GO:0005886 ; plasma membrane ( nanT )
GO:0006810 ; transport ( nanT )
GO:0008643 ; carbohydrate transport ( nanT )
GO:0015144 ; carbohydrate transmembrane transporter activity ( nanT )
GO:0015538 ; sialic acid:hydrogen ion symporter activity ( nanT )
GO:0015739 ; sialic acid transport ( nanT )
GO:0016020 ; membrane ( nanT )
GO:0016021 ; integral to membrane ( nanT )
 PID 87082231  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) NANT_ECOLI ( P41036 ; P76675 )
    -  Protein name Putative sialic acid transporter  
    -  Synonyms Sialic acid permease  
    -  Gene name Name=nanT; OrderedLocusNames=b3224;  

 Linear View (Whole Mode)
View Location
   3360.0  –  3385.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP nanT (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, Crystal Structure Of The Glycerol-3-Phosphate Transporter From E.Coli  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Putative sialic acid transporter  
         PSI-BLAST High-affinity glucose transporter SNF3
    nr     (database updated : 2007.02.20 )
         BLAST probable sialic acid transporter - Escherichia coli (strain K-12)  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE GLYCOSAMINOGLYCAN    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    TYR_PHOSPHO_SITE    MYRISTYL    AMIDATION    PROKAR_LIPOPROTEIN    LEUCINE_ZIPPER     

Other Cross-Reference
    EcoCyc nanT 

MMBR References
J Bacteriol. 1995;177:6005-6010
Derived structure of the putative sialic acid transporter from Escherichia coli predicts a novel sugar permease domain.
Martinez, J., S. Steenbergen, and E. Vimr.
J Bacteriol. 1985;164(2):845-53.
Identification of an inducible catabolic system for sialic acids (nan) in Escherichia coli.
Vimr ER, Troy FA. ( 3902799 )

Sequences
Amino acid
FASTA format 
0001 MSTTTQNIPW YRHLNRAQWR AFSAAWLGYL LDGFDFVLIA LVLTEVQGEF GLTTVQAASL ISAAFISRWF 
0071 GGLMLGAMGD RYGRRLAMVT SIVLFSAGTL ACGFAPGYIT MFIARLVIGM GMAGEYGSSA TYVIESWPKH 
0141 LRNKASGFLI SGFSVGAVVA AQVYSLVVPV WGWRALFFIG ILPIIFALWL RKNIPEAEDW KEKHAGKAPV 
0211 RTMVDILYRG EHRIANIVMT LAAATALWFC FAGNLQNAAI VAVLGLLCAA IFISFMVQSA GKRWPTGVML 
0281 MVVVLFAFLY SWPIQALLPT YLKTDLAYNP HTVANVLFFS GFGAAVGCCV GGFLGDWLGT RKAYVCSLLA 
0351 SQLLIIPVFA IGGANVWVLG LLLFFQQMLG QGIAGILPKL IGGYFDTDQR AAGLGFTYNV GALGGALAPI 
0421 IGALIAQRLD LGTALASLSF SLTFVVILLI GLDMPSRVQR WLRPEALRTH DAIDGKPFSG AVPFGSAKND 
0491 LVKTKS
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             ccctcgctcg cccctaccgg gtgaggggaa 
-070 ataaacgcat ctgtacccta caattttcat accaaagcgt gtgggcatcg cccaccgcgg gagactcaca 
0001 atgagtacta caacccagaa tatcccgtgg tatcgccatc tcaaccgtgc acaatggcgc gcattttccg 
0071 ctgcctggtt gggatatctg cttgacggtt ttgatttcgt tttaatcgcc ctggtactca ccgaagtaca 
0141 aggtgaattc gggctgacga cggtgcaggc ggcaagtctg atctctgcag cctttatctc tcgctggttc 
0211 ggcggcctga tgctcggcgc tatgggtgac cgctacgggc gtcgtctggc aatggtcacc agcatcgttc 
0281 tcttctcggc cgggacgctg gcctgcggct ttgcgccagg ctacatcacc atgtttatcg ctcgtctggt 
0351 catcggcatg gggatggcgg gtgaatacgg ttccagcgcc acctatgtca ttgaaagctg gccaaaacat 
0421 ctgcgtaaca aagccagtgg ttttttgatt tcaggcttct ctgtgggggc cgtcgttgcc gctcaggtct 
0491 atagcctggt ggttccggtc tggggctggc gtgcgctgtt ctttatcggc attttgccaa tcatctttgc 
0561 tctctggctg cgtaaaaaca tcccggaagc ggaagactgg aaagagaaac acgcaggtaa agcaccagta 
0631 cgcacaatgg tggatattct ctaccgtggt gaacatcgca ttgccaatat cgtaatgaca ctggcggcgg 
0701 ctactgcgct gtggttctgc ttcgccggta acctgcaaaa tgccgcgatc gtcgctgttc ttgggctgtt 
0771 atgcgccgca atctttatca gctttatggt gcagagtgca ggcaaacgct ggccaacggg cgtaatgctg 
0841 atggtggtcg tgttgtttgc tttcctctac tcatggccga ttcaggcgct gctgccaacg tatctgaaaa 
0911 ccgatctggc ttataacccg catactgtag ccaatgtgct gttctttagt ggctttggcg cggcggtggg 
0981 atgctgcgta ggtggcttcc tcggtgactg gctgggaacc cgcaaagcgt acgtttgtag cctgctggcc 
1051 tcgcagctgc tgattattcc ggtatttgcg attggcggcg caaacgtctg ggtgctcggt ctgttactgt 
1121 tcttccagca aatgcttgga caagggatcg ccgggatctt accaaaactg attggcggtt atttcgatac 
1191 cgaccagcgt gcagcgggcc tgggctttac ctacaacgtt ggcgcattgg gcggtgcact ggccccaatc 
1261 atcggcgcgt tgatcgctca acgtctggat ctgggtactg cgctggcatc gctctcgttc agtctgacgt 
1331 tcgtggtgat cctgctgatt gggctggata tgccttctcg cgttcagcgt tggttgcgcc cggaagcgtt 
1401 gcgtactcat gacgctatcg acggtaaacc attcagcggt gccgtgccgt ttggcagcgc caaaaacgat 
1471 ttagtcaaaa ccaaaagtta atcctgttgc ccggtctatg taccgggcct ttcgctaagg gaagatgtat 
1541 gtcgttactt gcacaactgg atcaaaaaat cgctgctaac ggtggcctga t