|
PEC Original Annotations
|
|
Essentiality
|
|
Class
|
non-essential
|
|
References (PMID)
|
Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
|
|
|
Deletion
|
4
(LD)
,
OCR13,15-3 (LD 4E_CRS)
(D)
,
OCR13,15-4 (LD 4E_P/O)
(D)
,
OCR15
(D)
|
|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
cadB
|
|
Related strains
|
|
Strains Search
|
Search strains by gene name:
cadB
Search strains by all related name:
cadB b4132 ECK4126 JW4093
|
General information (Go to Linear View: )
|
|
Gene Name
|
cadB
|
|
Alternative name
|
b4132,ECK4126,JW4093
|
|
Location, Length
|
4,356,720 - 4,358,054
(
-
)
;
93.90
min
;
1335
(bp) ,
444
(aa)
|
|
Product
|
putative lysine/cadaverine transporter
|
|
Operon Name
|
cadBA
|
|
Note
|
transport of lysine/cadaverine; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0009089 - lysine biosynthetic process via diaminopimelate
|
|
Function
|
transport; Transport of small molecules: Amino acids, amines
|
|
Gene Ontology
|
GO:0005886
;
plasma membrane ( cadB )
GO:0006810
;
transport ( cadB )
GO:0006865
;
amino acid transport ( cadB )
GO:0015171
;
amino acid transmembrane transporter activity ( cadB )
GO:0015297
;
antiporter activity ( cadB )
GO:0016020
;
membrane ( cadB )
GO:0016021
;
integral to membrane ( cadB )
|
|
PID
|
1790575
|
EC number
(KEGG Pathway)
|
|
|
SWISS-PROT
(
Show details
)
|
Entry name(Acc.no)
|
CADB_ECOLI
(
P23891
)
|
|
- Protein name
|
Probable cadaverine/lysine antiporter.
|
|
- Synonyms
|
|
|
- Gene name
|
Name=cadB; OrderedLocusNames=b4132, c5141, z5735, ECs5114;
|
|
Homology Analysis
|
|
BLAST
|
|
Bacteria
|
|
GTOP
|
cadB
(
homologous genes of other bacterias
)
|
|
PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Probable cadaverine/lysine antiporter
|
|
PSI-BLAST
|
Probable potassium transporter 2
|
|
nr
(database updated :
2007.02.20
)
|
|
BLAST
|
transport protein of lysine/cadaverine [Escherichia coli O157:H7 str. Sakai]
|
|
Pfam 28.0
(database updated :
2015-05
)
|
|
Pfam
|
|
|
PROSITE
|
|
PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
MYRISTYL
PROKAR_LIPOPROTEIN
|
|
MMBR References
|
J Bacteriol. 1992;174:2659-2669
Nucleotide sequence of the Escherichia coli cad operon: a system for neutralization of low extracellular pH.
Meng, S. Y., and G. N. Bennett.
|
J Bacteriol. 1996;178:5522-5528
Kinetics of expression of the Escherichia coli cad operon as a function of pH and lysine.
Neely, M. N., and E. R. Olson.
|
J Bacteriol. 1992;174:530-540
Identification of elements involved in transcriptional regulation of the Escherichia coli cad operon by external pH.
Watson, N., D. S. Dunyak, E. L. Rosey, J. L. Slonczewski, and E. R. Olson.
|
| Sequences |
Amino acid
FASTA format
|
0001 MSSAKKIGLF ACTGVVAGNM MGSGIALLPA NLASIGGIAI WGWIISIIGA MSLAYVYARL ATKNPQQGGP
0071 IAYAGEISPA FGFQTGVLYY HANWIGNLAI GITAVSYLST FFPVLNDPVP AGIACIAIVW VFTFVNMLGG
0141 TWVSRLTTIG LVLVLIPVVM TAIVGWHWFD AATYAANWNT ADTTDGHAII KSILLCLWAF VGVESAAVST
0211 GMVKNPKRTV PLATMLGTGL AGIVYIAATQ VLSGMYPSSV MAASGAPFAI SASTILGNWA APLVSAFTAF
0281 ACLTSLGSWM MLVGQAGVRA ANDGNFPKVY GEVDSNGIPK KGLLLAAVKM TALMILITLM NSAGGKASDL
0351 FGELTGIAVL LTMLPYFYSC VDLIRFEGVN IRNFVSLICS VLGCVFCFIA LMGASSFELA GTFIVSLIIL
0421 MFYARKMHER QSHSMDNHTA SNAH
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ttttttcgtg agtaatctta tcgccagttt
-070 ggtctggtca ggaaatagtt atacatcatg acccggactc caaattcaaa aatgaaatta ggagaagagc
0001 atgagttctg ccaagaagat cgggctattt gcctgtaccg gtgttgttgc cggtaatatg atggggagcg
0071 gtattgcatt attacctgcg aacctagcaa gtatcggtgg tattgctatc tggggttgga ttatctctat
0141 tattggtgca atgtcgctgg cgtatgtata tgcccgactg gcaacaaaaa acccgcaaca aggtggccca
0211 attgcttatg ccggagaaat ttcccctgca tttggttttc agacaggtgt tctttattac catgctaact
0281 ggattggtaa cctggcgatt ggtattaccg ctgtatctta tctttccacc ttcttcccag tattaaatga
0351 tcctgttccg gcgggtatcg cctgtattgc tatcgtctgg gtatttacct ttgtaaatat gctcggcggt
0421 acttgggtaa gccgtttaac cactattggt ctggtgctgg ttcttattcc tgtggtgatg actgctattg
0491 ttggctggca ttggtttgat gcggcaactt atgcagctaa ctggaatact gcggatacca ctgatggtca
0561 tgcgatcatt aaaagtattc tgctctgcct gtgggccttc gtgggtgttg aatccgcagc tgtaagtact
0631 ggtatggtta aaaacccgaa acgtaccgtt ccgctggcaa ccatgctggg tactggttta gcaggtattg
0701 tttacatcgc tgcgactcag gtgctttccg gtatgtatcc gtcttctgta atggcggctt ccggtgctcc
0771 gtttgcaatc agtgcttcaa ctatcctcgg taactgggct gcgccgctgg tttctgcatt caccgccttt
0841 gcgtgcctga cttctctggg ctcctggatg atgttggtag gccaggcagg tgtacgtgcc gctaacgacg
0911 gtaacttccc gaaagtttat ggtgaagtcg acagcaacgg tattccgaaa aaaggtctgc tgctggctgc
0981 agtgaaaatg actgccctga tgatccttat cactctgatg aactctgccg gtggtaaagc atctgacctg
1051 ttcggtgaac tgaccggtat cgcagtactg ctgactatgc tgccgtattt ctactcttgc gttgacctga
1121 ttcgttttga aggcgttaac atccgcaact ttgtcagcct gatctgctct gtactgggtt gcgtgttctg
1191 cttcatcgcg ctgatgggcg caagctcctt cgagctggca ggtaccttca tcgtcagcct gattatcctg
1261 atgttctacg ctcgcaaaat gcacgagcgc cagagccact caatggataa ccacaccgcg tctaacgcac
1331 attaattaaa agtattttcc gaggctcctc ctttcatttt gtcccatgtg ttgggagggg ccttttttac
1401 ctggagatat gactatgaac gttattgcaa tattg
|
