MG1655
W3110
Search for
Japanese | English
Top Genes Deletions Circular Linear Motif Contigs BLAST Reference SequenceCutter Download Strains TEC
Gene Report : fepD
PEC Original Annotations
Essentiality
     Class non-essential
     References (PMID)
J Bacteriol. 1987;169(8):3638-46.
Genetic organization of multiple fep genes encoding ferric enterobactin transport functions in Escherichia coli.
Ozenberger BA, Nahlik MS, McIntosh MA. ( 2956250 )
     Deletion OCR44,45-2 (LD 12-1_P/O) (D)  ,  OCR45 (D)  
Related gene (W3110 PEC)
     Gene Search Search MG1655 PEC by gene name:  fepD
Related strains
     Strains Search Search strains by gene name:  fepD   Search strains by all related name:  fepD b0590 ECK0583 JW0582

General information  (Go to Linear View:)
 Gene Name fepD  
 Alternative name b0590,ECK0583,JW0582  
 Location, Length 620,408 - 621,412 (  -  ) ;   13.37 min ; 1005 (bp) ,   334 (aa) Go to Linear View
 Product iron-enterobactin transporter subunit  
 Operon Name fepDGC  
 Note ferric enterobactin (enterochelin) transport; membrane component of ABC superfamily; GO_component: GO:0009274 - peptidoglycan-based cell wall; GO_component: GO:0019866 - organelle inner membrane; GO_process: GO:0006826 - iron ion transport  
 Function transport; Transport of small molecules: Cations  
 Gene Ontology GO:0005215 ; transporter activity ( fepD )
GO:0005506 ; iron ion binding ( fepD )
GO:0005886 ; plasma membrane ( fepD )
GO:0006810 ; transport ( fepD )
GO:0006811 ; ion transport ( fepD )
GO:0006826 ; iron ion transport ( fepD )
GO:0016020 ; membrane ( fepD )
GO:0016021 ; integral to membrane ( fepD )
 PID 1786805  
 EC number
  (KEGG Pathway)   		 
SWISS-PROT  ( Show details [ 2 more] )
  botton Entry name(Acc.no) FEPD_ECOLI ( P23876 ; P77097 )
    -  Protein name Ferric enterobactin transport system permease protein fepD.  
    -  Synonyms  
    -  Gene name Name=fepD; OrderedLocusNames=b0590;  

 Linear View (Whole Mode)
View Location
   610.0  –  635.0 (KBP)

Homology Analysis
BLAST
    Bacteria
         GTOP fepD (  homologous genes of other bacterias  )  
    PDB     (database updated : 2007.02.20 )
         PSI-BLAST Chain A, An Inward-Facing Conformation Of A Putative Metal-Chelate Type Abc Transporter.  
    SWISS-PROT     (database updated : 2007.02.20 )
         BLAST Ferric enterobactin transport system permease protein fepD  
         PSI-BLAST Ferrichrome transport system permease protein fhuB
    nr     (database updated : 2007.02.20 )
         BLAST ferric enterobactin transport protein [Escherichia coli]  
Pfam 28.0   (database updated : 2015-05 )
    Pfam
PROSITE
    PROSITE CAMP_PHOSPHO_SITE    PKC_PHOSPHO_SITE    CK2_PHOSPHO_SITE    MYRISTYL    LEUCINE_ZIPPER     

Other Cross-Reference
    COG COG0609P 
    EcoCyc fepD 

MMBR References
J Bacteriol. 1994;176:3944-3955
Promoter and operator determinants for Fur-mediated iron regulation in the bidirectional fepA-fes control region of the Escherichia coli enterobactin gene system.
Hunt, M. D., G. S. Pettis, and M. A. McIntosh.
J Bacteriol. 1987;169(8):3638-46.
Genetic organization of multiple fep genes encoding ferric enterobactin transport functions in Escherichia coli.
Ozenberger BA, Nahlik MS, McIntosh MA. ( 2956250 )
Mol Microbiol. 1991;5(6):1415-28.
Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli.
Shea CM, McIntosh MA. ( 1838574 )

Sequences
Amino acid
FASTA format 
0001 MSGSVAVTRA IAVPGLLLLL IIATALSLLI GAKSLPASVV LEAFSGTCQS ADCTIVLDAR LPRTLAGLLA 
0071 GGALGLAGAL MQTLTRNPLA DPGLLGVNAG ASFAIVLGAA LFGYSSAQEQ LAMAFAGALV ASLIVAFTGS 
0141 QGGGQLSPVR LTLAGVALAA VLEGLTSGIA LLNPDVYDQL RFWQAGSLDI RNLHTLKVVL IPVLIAGATA 
0211 LLLSRALNSL SLGSDTATAL GSRVARTQLI GLLAITVLCG SATAIVGPIA FIGLMMPHMA RWLVGADHRW 
0281 SLPVTLLATP ALLLFADIIG RVIVPGELRV SVVSAFIGAP VLIFLVRRKT RGGA
Nucleotide
FASTA format

View sequence out neighbor 100bp 
-100                                             tgccatcaaa tattttaaat acctattctt 
-070 aggctgcaca tgctaacata tccaaataag atcgataacg ataattaatt tcattatcat ggaagttcgt 
0001 atgtctggtt ctgttgccgt gacacgcgcc attgccgtgc ccggattgct gttattactg attatcgcga 
0071 cggcattaag cctgctcatt ggggcaaaat cactccccgc ttccgtagtg ctggaggcct tctccggcac 
0141 ctgccagagc gccgactgca ccatcgtgct cgacgcgcgg ctgccgcgta cccttgccgg tttactggca 
0211 ggcggcgcgc ttggccttgc cggggcgtta atgcaaaccc tcacccgaaa cccacttgcc gaccccggct 
0281 tgcttggcgt gaacgccgga gccagctttg ccattgtgct gggtgcggcg ctgtttggtt actcttccgc 
0351 gcaggaacaa ctggcgatgg ccttcgccgg ggcgctggtg gcctcattga ttgttgcctt taccggcagt 
0421 cagggcggcg ggcagttaag tccggtgcgt ttaaccctgg cgggcgtggc gctggcggcg gtgctggaag 
0491 gactgaccag cggcatcgcc ctgcttaatc ctgacgtcta cgatcagttg cgtttctggc aagccggttc 
0561 gctggatatt cgcaatctac ataccttaaa agtggtgctg atcccggtgc tgatcgccgg agcaactgcg 
0631 ctattactga gtcgcgcgct gaacagtttg agcctcggca gcgacaccgc gacggcgctg ggcagtcgcg 
0701 tggcgcgcac acagttgatt ggtctgctgg cgattaccgt gctttgtggt agtgcgacgg caatagttgg 
0771 cccgattgcc tttattggcc tgatgatgcc gcatatggcg cgttggctgg tgggtgccga tcatcgctgg 
0841 tcgctgcccg tcacgctact tgctacccct gccctgctgc tgtttgccga tatcatcggg cgggtgattg 
0911 tgcccggcga actgcgcgtt tctgtggtca gtgcgtttat tggtgcaccg gtgctgatct tcctcgtgcg 
0981 acgtaaaacg cgaggtggtg catgatttac gtctctcgcc gattactcat cacctgtttg ctgctggttt 
1051 ccgcctgtgt ggttgcaggt atctggggat tacgcagcgg tgccgtcacg ctgga