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PEC Original Annotations
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|
Essentiality
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Class
|
non-essential
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|
References (PMID)
|
Mol Microbiol. 1991;5(6):1405-13.
Organization of genes encoding membrane proteins of the Escherichia coli ferrienterobactin permease.
Chenault SS, Earhart CF.
(
1787794
)
|
|
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Deletion
|
OCR44,45-2 (LD 12-1_P/O)
(D)
,
OCR45
(D)
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|
Related gene (W3110 PEC)
|
|
Gene Search
|
Search MG1655 PEC by gene name:
fepB
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|
Related strains
|
|
Strains Search
|
Search strains by gene name:
fepB
Search strains by all related name:
fepB b0592 ECK0585 JW0584
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General information (Go to Linear View: )
|
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Gene Name
|
fepB
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Alternative name
|
b0592,ECK0585,JW0584
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|
Location, Length
|
622,777 - 623,733
(
-
)
;
13.42
min
;
957
(bp) ,
318
(aa)
|
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Product
|
iron-enterobactin transporter subunit
|
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Operon Name
|
fepB
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Note
|
ferric enterobactin (enterochelin) binding protein; periplasmic component; periplasmic-binding component of ABC superfamily; GO_component: GO:0042597 - periplasmic space; GO_process: GO:0006826 - iron ion transport
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|
Function
|
transport; Transport of small molecules: Cations
|
|
Gene Ontology
|
GO:0005381
;
iron ion transmembrane transporter activity ( fepB )
GO:0005506
;
iron ion binding ( fepB )
GO:0006810
;
transport ( fepB )
GO:0006811
;
ion transport ( fepB )
GO:0006826
;
iron ion transport ( fepB )
GO:0006827
;
high-affinity iron ion transport ( fepB )
GO:0042597
;
periplasmic space ( fepB )
|
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PID
|
1786807
|
EC number
(KEGG Pathway)
|
|
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Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
|
EcoGene
|
fepB
(
EG10294
)
|
|
Number of removed
|
26 aa cleaved
|
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SWISS-PROT
(
Show details
[
1
more]
)
|
Entry name(Acc.no)
|
FEPB_ECOLI
(
P14609
)
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|
- Protein name
|
Ferrienterobactin-binding periplasmic protein precursor.
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- Synonyms
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- Gene name
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Name=fepB; OrderedLocusNames=b0592, c0679;
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Homology Analysis
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BLAST
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Bacteria
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GTOP
|
fepB
(
homologous genes of other bacterias
)
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PDB
(database updated :
2007.02.20
)
|
|
PSI-BLAST
|
Chain A, Ceue In Complex With Mecam
|
|
SWISS-PROT
(database updated :
2007.02.20
)
|
|
BLAST
|
Ferrienterobactin-binding periplasmic protein precursor
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|
PSI-BLAST
|
Ferrienterobactin-binding periplasmic protein precursor
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|
nr
(database updated :
2007.02.20
)
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BLAST
|
iron-enterobactin transporter subunit [Escherichia coli K12]
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Pfam 28.0
(database updated :
2015-05
)
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Pfam
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PROSITE
|
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PROSITE
|
ASN_GLYCOSYLATION
PKC_PHOSPHO_SITE
CK2_PHOSPHO_SITE
TYR_PHOSPHO_SITE
MYRISTYL
AMIDATION
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MMBR References
|
J Bacteriol. 1987;169(8):3638-46.
Genetic organization of multiple fep genes encoding ferric enterobactin transport functions in Escherichia coli.
Ozenberger BA, Nahlik MS, McIntosh MA.
(
2956250
)
|
J Bacteriol. 1986;166(3):930-6.
Escherichia coli K-12 envelope proteins specifically required for ferrienterobactin uptake.
Pierce JR, Earhart CF.
(
3011753
)
|
J Bacteriol. 1983;155(1):330-6.
Two fep genes are required for ferrienterochelin uptake in Escherichia coli K-12.
Pierce JR, Pickett CL, Earhart CF.
(
6223021
)
|
Mol Microbiol. 1991;5(6):1415-28.
Nucleotide sequence and genetic organization of the ferric enterobactin transport system: homology to other periplasmic binding protein-dependent systems in Escherichia coli.
Shea CM, McIntosh MA.
(
1838574
)
|
Microbiology 1995;141:1647-1654
Escherichia coli periplasmic protein FepB binds ferrienterobactin.
Stephens, D. L., M. D. Choe, and C. F. Earhart.
|
J Bacteriol. 1978;133(2):661-6.
Involvement of inner and outer membrane components in the transport of iron and in colicin B action in Escherichia coli.
Wookey P, Rosenberg H.
(
146699
)
|
Mol Gen Genet. 1983;192(1-2):131-9.
Plasmid and chromosomal mutants in the iron(III)-aerobactin transport system of Escherichia coli. Use of streptonigrin for selection.
Braun V, Gross R, Koster W, Zimmermann L.
(
6316109
)
|
J Mol Biol. 1990;212(4):669-82.
Regulation of divergent transcription from the iron-responsive fepB-entC promoter-operator regions in Escherichia coli.
Brickman TJ, Ozenberger BA, McIntosh MA.
(
2139473
)
|
| Sequences |
Amino acid
FASTA format
|
0001 MRLAPLYRNA LLLTGLLLSG IAAVQAADWP RQITDSRGTH TLESQPQRIV STSVTLTGSL LAIDAPVIAS
0071 GATTPNNRVA DDQGFLRQWS KVAKERKLQR LYIGEPSAEA VAAQMPDLIL ISATGGDSAL ALYDQLSTIA
0141 PTLIINYDDK SWQSLLTQLG EITGHEKQAA ERIAQFDKQL AAAKEQIKLP PQPVTAIVYT AAAHSANLWT
0211 PESAQGQMLE QLGFTLAKLP AGLNASQSQG KRHDIIQLGG ENLAAGLNGE SLFLFAGDQK DADAIYANPL
0281 LAHLPAVQNK QVYALGTETF RLDYYSAMQV LDRLKALF
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 tcaccctaac cctctcccca aaggggcgag
-070 gggacggatt gtgcgctttg tcgaatttgt cattacgccc ttaaccttat taataacagg aagctgattt
0001 gtgagactcg ccccgctcta ccgcaacgcc cttctattaa caggactttt gctttcagga atagccgcag
0071 ttcaggccgc tgactggccg cgtcagatta ctgacagccg tggcacacat acactggaaa gccagccgca
0141 gcgtattgtt tccaccagcg tcaccctgac cggctcactg ctggcgattg atgctccggt gatcgccagc
0211 ggcgcgacca cgccgaataa ccgcgtcgcg gatgaccagg gctttttacg ccagtggagc aaggtggcga
0281 aagaacgcaa actgcaacgg ctctatatcg gcgaaccgag cgccgaagcc gttgccgcgc aaatgccgga
0351 tctgatttta attagcgcaa ccggcgggga ttcggcgctg gcactgtatg atcagctttc caccatcgcc
0421 ccgacattaa tcatcaatta cgacgacaaa agctggcagt cgctgttaac gcaacttggc gaaattaccg
0491 ggcatgagaa acaagcggca gagcggattg cgcagtttga taagcaactg gcggcggcga aagagcaaat
0561 caaattaccg ccgcagccgg tcactgccat tgtctatact gccgctgcac acagtgccaa tctctggacg
0631 ccagaatcag cacaagggca gatgctggaa caactcggct ttacgctggc gaagttaccc gcagggttaa
0701 atgccagcca aagtcagggt aaacgccatg acatcattca gcttggtggg gaaaatctgg ctgcagggtt
0771 aaatggcgag tcactattcc tgttcgccgg tgatcagaaa gatgccgatg ctatttatgc taatccgctg
0841 ctcgcgcacc tgcctgcagt acaaaacaag caggtttatg cgctgggaac cgagacgttc cgtctggatt
0911 actacagcgc catgcaagtg ctggataggc ttaaggcgct gttttaagca ttaactgtcg gacgctgtca
0981 cctgcggcgg cgtctggcga aaatgtcgca actccaccag caccagcaat aacaacacgc cgataatcaa
1051 caaacca
|
