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PEC Original Annotations
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Essentiality
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Class
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non-essential
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References (PMID)
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Escherichia coli and Salmonella, Cellular and Molecular Biology Second Edition. ASM Press. 1996
Neidhart, F.C.
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Deletion
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OCR47,48-1
(D)
,
OCR47-15 (BK5-3 / AK4-3-29)
(D)
,
OCR47-3
(D)
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Related gene (W3110 PEC)
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Gene Search
|
Search MG1655 PEC by gene name:
nagC
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Related strains
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Strains Search
|
Search strains by gene name:
nagC
Search strains by all related name:
nagC b0676 ECK0664 JW0662 nagR
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General information (Go to Linear View: )
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Gene Name
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nagC
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Alternative name
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b0676,ECK0664,JW0662,nagR
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Location, Length
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699,597 - 700,817
(
-
)
;
15.08
min
;
1221
(bp) ,
406
(aa)
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Product
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DNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine
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Operon Name
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nagBACD
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Note
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transcriptional repressor of nag (N-acetylglucosamine) operon; GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_function: GO:0016564 - transcription repressor activity; GO_process: GO:0046349 - amino sugar biosynthetic process; GO_process: GO:0006350 - transcription; GO_process: GO:0009386 - translational attenuation
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Function
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regulator; Central intermediary metabolism: Amino sugars
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Gene Ontology
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GO:0003677
;
DNA binding ( nagC )
GO:0003700
;
transcription factor activity ( nagC )
GO:0005622
;
intracellular ( nagC )
GO:0005975
;
carbohydrate metabolic process ( nagC )
GO:0006350
;
transcription ( nagC )
GO:0006355
;
regulation of transcription, DNA-dependent ( nagC )
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PID
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1786891
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EC number
(KEGG Pathway)
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SWISS-PROT
(
Show details
)
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Entry name(Acc.no)
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NAGC_ECOLI
(
P15301
)
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- Protein name
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N-acetylglucosamine repressor.
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- Synonyms
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- Gene name
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OrderedLocusNames=b0676, c0751, z0823, ECs0706, SF0617, S0628;
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MMBR References
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Biochem Cell Biol. 1990;68(1):123-37.
Cloning and characterization of the N-acetylglucosamine operon of Escherichia coli.
Peri KG, Goldie H, Waygood EB.
(
2190615
)
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Mol Microbiol. 1989;3(4):505-15.
Sequence of the nagBACD operon in Escherichia coli K12 and pattern of transcription within the nag regulon.
Plumbridge JA.
(
2668691
)
|
J Bacteriol. 1990;172(5):2728-35.
Induction of the nag regulon of Escherichia coli by N-acetylglucosamine and glucosamine: role of the cyclic AMP-catabolite activator protein complex in expression of the regulon.
Plumbridge JA.
(
2158978
)
|
Mol Microbiol. 1991;5(8):2053-62.
Repression and induction of the nag regulon of Escherichia coli K-12: the roles of nagC and nagA in maintenance of the uninduced state.
Plumbridge JA.
(
1766379
)
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J Gen Microbiol. 1992;138(5):1011-7.
A dominant mutation in the gene for the Nag repressor of Escherichia coli that renders the nag regulon uninducible.
Plumbridge JA.
(
1645125
)
|
J Bacteriol. 1995;177:5918-5923
Kinetic characterization of 4-amino 4-deoxychorismate synthase from Escherichia coli.
Viswanathan, V. K., J. M. Green, and B. P. Nichols.
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| Sequences |
Amino acid
FASTA format
|
0001 MTPGGQAQIG NVDLVKQLNS AAVYRLIDQY GPISRIQIAE QSQLAPASVT KITRQLIERG LIKEVDQQAS
0071 TGGRRAISIV TETRNFHAIG VRLGRHDATI TLFDLSSKVL AEEHYPLPER TQQTLEHALL NAIAQFIDSY
0141 QRKLRELIAI SVILPGLVDP DSGKIHYMPH IQVENWGLVE ALEERFKVTC FVGHDIRSLA LAEHYFGASQ
0211 DCEDSILVRV HRGTGAGIIS NGRIFIGRNG NVGEIGHIQV EPLGERCHCG NFGCLETIAA NAAIEQRVLN
0281 LLKQGYQSRV PLDDCTIKTI CKAANKGDSL ASEVIEYVGR HLGKTIAIAI NLFNPQKIVI AGEITEADKV
0351 LLPAIESCIN TQALKAFRTN LPVVRSELDH RSAIGAFALV KRAMLNGILL QHLLEN
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Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 ccgcaggtaa agtagccaac ctgactgcat
-070 tcacacctga ttttaaaatc accaagacca tcgttaacgg taacgaggtc gtaactcaat aagagaaagt
0001 atgacaccag gcggacaagc tcagataggt aatgttgatc tcgtaaaaca gcttaacagc gcggcggttt
0071 atcgcctgat tgaccagtac gggccaatct cgcggattca gattgccgag caaagccagc ttgcccccgc
0141 cagcgtaacc aaaattacgc gtcagcttat cgaacgcggg ctgatcaaag aagttgatca gcaggcctcc
0211 accgggggcc gccgcgctat ctccatcgtc accgaaaccc gcaatttcca cgcaatcggc gtacggcttg
0281 gtcgtcatga cgccaccatc actctgtttg atctcagcag caaagtgctg gcagaagaac attacccgct
0351 gccggaacgt acccagcaaa cgctggaaca tgccctgttg aatgccattg ctcagtttat tgatagctac
0421 cagcgcaaac tgcgcgagct gatcgcgatt tcggtgatcc tgccagggct tgttgacccg gacagcggca
0491 aaattcatta catgccgcat attcaggtag aaaactgggg gctggtagaa gctctggaag aacgttttaa
0561 agtgacctgt ttcgttggtc acgatatccg tagtctggcg ctggcggagc actacttcgg tgcaagtcag
0631 gattgcgaag actccattct ggtgcgtgtc catcgcggaa ccggggccgg gattatctct aacgggcgca
0701 tttttattgg ccgcaacggc aacgtcggtg aaattggcca tattcaggtc gaaccgctgg gtgaacgctg
0771 ccactgcggc aactttggct gcctggaaac tatcgctgcc aacgctgcca ttgaacaacg ggtgttgaat
0841 ctgttaaagc agggctacca gagccgcgtg ccgctggacg actgcaccat caaaactatc tgcaaagccg
0911 cgaacaaagg cgatagtctg gcgtcggaag taattgagta tgtcggtcgt catctgggta aaaccatcgc
0981 cattgctatc aacttattta atccgcaaaa aattgttatt gccggtgaaa tcaccgaagc cgataaagtg
1051 ctgctccctg ctattgaaag ctgcattaat acccaggcgc tgaaggcgtt tcgcactaat ctgccggtgg
1121 tacgttctga gctggatcac cgctcggcaa tcggcgcttt tgcgctggta aaacgcgcca tgctcaacgg
1191 tattttgctc cagcatttgc tggaaaatta atgtgctttt atagtggcgc ttattgttgt caatattctg
1261 ggtagtccat gaccattaaa aatgtaattt gcgatatcga cggcgtgctg atgcacgata a
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