PEC Original Annotations
|
Essentiality
|
Class
|
non-essential
|
References (PMID)
|
|
Deletion
|
DE(pgl-grxA)502
,
OCR48,49-8
(D)
|
Related gene (W3110 PEC)
|
Gene Search
|
Search MG1655 PEC by gene name:
kdpE
|
Related strains
|
Strains Search
|
Search strains by gene name:
kdpE
Search strains by all related name:
kdpE b0694 ECK0682 JW5096
|
General information (Go to Linear View:)
|
Gene Name
|
kdpE
|
Alternative name
|
b0694,ECK0682,JW5096
|
Location, Length
|
720,279 - 720,956
(
-
)
;
15.52
min
;
678
(bp) ,
225
(aa)
|
Product
|
DNA-binding response regulator in two-component regulatory system with KdpD
|
Operon Name
|
kdpDE
|
Note
|
regulator of kdp operon (transcriptional effector); GO_component: GO:0005737 - cytoplasm; GO_function: GO:0016563 - transcription activator activity; GO_process: GO:0006350 - transcription
|
Function
|
regulator; Global regulatory functions
|
Gene Ontology
|
GO:0000156
;
two-component response regulator activity ( kdpE )
GO:0000160
;
two-component signal transduction system (phosphorelay) ( kdpE )
GO:0003677
;
DNA binding ( kdpE )
GO:0005737
;
cytoplasm ( kdpE )
GO:0006350
;
transcription ( kdpE )
GO:0006355
;
regulation of transcription, DNA-dependent ( kdpE )
|
PID
|
1786911
|
EC number
(KEGG Pathway)
|
|
Verified Protein Starts
(data
compiled from literature and appropriate citations are available from EcoGene)
|
EcoGene
|
kdpE
(
EG10517
)
|
Number of removed
|
0 aa cleaved
|
SWISS-PROT
(
Show details
[
2
more]
)
|
Entry name(Acc.no)
|
KDPE_ECOLI
(
P21866
;
P75739; P76822
)
|
- Protein name
|
KDP operon transcriptional regulatory protein kdpE.
|
- Synonyms
|
|
- Gene name
|
Name=kdpE; OrderedLocusNames=b0694;
|
MMBR References
|
J Bacteriol. 1993;175:4528-4537
Regulation of kdp operon expression in Escherichia coli: evidence against turgor as signal for transcriptional control.
Asha, H., and J. Gowrishankar.
|
Mol Microbiol. 1993;7(1):109-16.
Signal transduction between the two regulatory components involved in the regulation of the kdpABC operon in Escherichia coli: phosphorylation-dependent functioning of the positive regulator, KdpE.
Nakashima K, Sugiura A, Kanamaru K, Mizuno T.
(
8437514
)
|
J. Biochem. (Tokyo) 1993;114:615-621
Functional reconstitution of the putative Escherichia coli osmosensor, KdpD, into liposomes.
Nakashima, K., A. Sugiura, and T. Mizuno.
|
J Bacteriol. 1992;174:2145-2151
The products of the kdpDE operon are required for expression of the Kdp ATPase of Escherichia coli.
Polarek, J. W., G. Williams, and W. Epstein.
|
Mol Microbiol. 1992;6(13):1769-76.
Clarification of the structural and functional features of the osmoregulated kdp operon of Escherichia coli.
Sugiura A, Nakashima K, Tanaka K, Mizuno T.
(
1630316
)
|
Eur J Biochem. 1993;217:1019-1026
Characterization of the KdpD protein, the sensor kinase of the K+-translocating Kdp system of Escherichia coli.
Voelkner, P., W. Puppe, and K. Altendorf.
|
J Bacteriol. 1992;174:2152-2159
KdpD and KdpE, proteins that control expression of the kdpABC operon, are members of the two-component sensor-effector class of regulators.
Walderhaug, M. O., J. W. Polarek, P. Voelkner, J. Daniel, J. E. Hesse, K. Altendorf, and W. Epstein.
|
Sequences |
Amino acid
FASTA format
|
0001 MTNVLIVEDE QAIRRFLRTA LEGDGMRVFE AETLQRGLLE AATRKPDLII LDLGLPDGDG IEFIRDLRQW
0071 SAVPVIVLSA RSEESDKIAA LDAGADDYLS KPFGIGELQA RLRVALRRHS ATTAPDPLVK FSDVTVDLAA
0141 RVIHRGEEEV HLTPIEFRLL AVLLNNAGKV LTQRQLLNQV WGPNAVEHSH YLRIYMGHLR QKLEQDPARP
0211 RHFITETGIG YRFML
|
Nucleotide
FASTA format
View sequence out neighbor 100bp
|
-100 gcactattac cgcgttcaac cgaccggaag
-070 gtggtgcctg ttttcgtgtt acacttcccc agcaaactgc ccctgaactt gaagaatttc atgaggatat
0001 gtgacaaacg ttctgattgt tgaagatgaa caggctattc gtcgctttct gcgcacggcg ctggagggcg
0071 acgggatgcg cgtctttgag gccgaaacgc tgcaacgcgg cttgctggaa gcggcaaccc gtaagccaga
0141 tttgattatt ctcgatctcg gcctgcccga tggtgatggg attgagttta tccgcgacct gcgccagtgg
0211 agcgcggtgc cggtgattgt gctttccgca cgcagcgaag agagcgacaa aatcgccgcg ctggatgccg
0281 gagcggatga ttatctgagt aagccgtttg gcattggcga attgcaggcc cgtctgcgcg tcgcattacg
0351 ccgccactct gccaccaccg cgcccgatcc gctggtaaaa ttttccgatg ttaccgtcga tttagccgcc
0421 cgcgtgattc accggggtga ggaagaggtg catctcacac caattgagtt ccgcctgctg gcggtgctgc
0491 tcaacaatgc cggaaaagta ctcacccagc gccagctcct taaccaggtg tgggggccaa acgcggtcga
0561 acacagtcac tatttgcgta tttatatggg acatctgcga caaaaactgg aacaggatcc cgcccgccca
0631 cgccatttca ttactgaaac cggtattggc tatcggttta tgctttgaat attaatttta atacagcctg
0701 ccttttatta attaaagccg taataataaa tacggctttt tatcttaaac aacacacaaa aataacaatt
0771 caatattt
|